N. Levashov's «SvetL Broom» in A. Khatybov's «Bath School» Book 3. The Cell and Health

Book 3. The Cell and Health. Chapter 1. The Cell – interaction in harmony 24 Life is impossible without the mechanism of its reproduction, carried out by replication. In the experiments of Julius Rebek , it was shown that not only cells but also molecules possess the property of replication. For the replication process, DNA and RNA (as carriers and transmitters of information) and enzymes (i.e., proteins) are needed to accelerate the reaction. From the point of view of "chemical evolution" this gives rise to the classical paradox of a chicken or an egg primacy: for the appearance of protein, DNA and RNA replication is necessary, and proteins are necessary for replication of DNA and RNA . What is the way to solve this problem? American scientists Orgel and Jason experimentally demonstrated the possibility of replicating the entire molecule of DNA and RNA without participation of enzymes (however, only under ideal conditions). The Swiss chemist Eschenmuser in his experiments showed "step by step" (that is, link after link) replication of DNA and RNA under natural conditions. So, the mystery of the life origin is revealed, isn’t it? However, careful analysis reveals a number of problems. Of the many biological substances present in the cells, only two are similar to those obtained in Miller-type experiments – they are glycine and alanine. But the rest of the substances that make up the living cell have never been obtained. They could not have been "obtained" for the reasons described in the previous chapters regarding the Ebr possibilities in the knowledge of physics of the cell. Herbert Ling’s 3 hypothesis is only breaking through, so A. Oparin’s hypothesis remains basic at the present stage in the development of "scientific understanding". But it requires the search for mechanisms capable of resolving the colossal contradiction between the fact of existence of life and an extremely low probability of its accidental origin: so that "life" could originate out of ordinary molecules under certain conditions and then exist under any conditions, the molecules of which "it" consists should be able to continuously create these conditions and reproduce themselves. And at the same time, so that to match the properties 3 "The physical theory of a living cell: an unnoticed revolution."